Progressive pulmonary fibrosis is caused by elevated mechanical tension on alveolar stem cells

نویسندگان

چکیده

(Cell 180, 107–121.e1–e17; January 9, 2020) In our paper we showed that the periphery-to-center progression of lung fibrosis is driven by a TGF-β signaling loop activated mechanical tension in alveolar stem cells. It has come to attention Figure 5F image selected represent cells from stretched+GSK3008348 condition came non-stretched control was inadvertently mislabeled. This error now been corrected using an acquired raw data, which properly labeled. The quantification shown 5G reflects data and not affected this error. new version figure consistent with reported conclusions. We sincerely apologize for any confusion may have caused.Figure 5Elevated Mechanical Tension Activates Signaling AT2 Cells (original)View Large Image ViewerDownload Hi-res Download (PPT) Progressive Pulmonary Fibrosis Is Caused Elevated on Alveolar Stem CellsWu et al.CellDecember 19, 2019In BriefBy investigating links between impaired regeneration progressive pulmonary fibrosis, Wu al. found most common type sustained elevated activates Full-Text PDF Open Archive

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ژورنال

عنوان ژورنال: Cell

سال: 2021

ISSN: ['0092-8674', '1097-4172']

DOI: https://doi.org/10.1016/j.cell.2021.01.020